The Global Fund to Fight AIDS, Tuberculosis and Malaria emerged from international efforts in the early 2000s to mobilize substantially greater resources against three devastating infectious diseases. Established in 2002, the Geneva-based organization operates as a multilateral financing partnership rather than a traditional implementing agency, bringing together governments, affected communities, civil society, foundations, businesses and technical organizations. Countries receiving support help determine their own priorities and how investments should be deployed.

Funding is directed toward prevention, diagnosis, treatment and care for HIV, tuberculosis and malaria, alongside stronger health and community systems. The Global Fund also uses its purchasing power to expand access to medicines, diagnostics and other essential health products, while supporting local health workers and community organizations. Since its creation, its partnership has invested more than $69 billion and reports saving 70 million lives across more than 100 countries, making it the largest multilateral funder of global health grants to low- and middle-income countries.